Thursday, March 7, 2013

Inhibiting protein prevents metastasis to lungs in mice

Wednesday, March 6, 2013

Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation factor 6 (ARF6) reduces the spread of melanoma to the lungs in mice, according to a study published in the March 5 issue of Science Signaling online, suggesting that targeting ARF6 may be an effective approach to preventing melanoma metastasis.

Melanoma is the sixth most common cancer in the United States. Approximately one in 50 people will develop melanoma in their lifetime, and the number of melanoma cases diagnosed each year is increasing faster than for any other cancer. While melanoma generally starts as a single skin tumor, cancer cells can spread, or metastasize, to distant sites throughout the body such as the liver, lungs, and brain.

"Metastasis is what makes melanoma lethal, but our knowledge of how melanoma spreads is limited," says Allie Grossmann, M.D., Ph.D., molecular genetic pathology fellow at the University of Utah and co-first author on the study. "By improving our understanding of the cellular machinery responsible for melanoma metastasis, we can better identify targeted therapies that may stop the spread of cancer cells."

Although significant progress has been made in the treatment of metastatic melanoma, currently available treatments still can't achieve long-term survivorship in most patients. Grossmann and her colleagues discovered a new molecular pathway involving ARF6 that promotes metastasis and can be inhibited by a small molecule known as SecinH3.

"The surprising discovery that SecinH3 seems to inhibit the entire metastatic signaling cascade represents a potential breakthrough that may lead to improvements in the efficacy of current drug therapy. Our findings are exciting because the clinical implications extend beyond melanoma to other cancers, such as breast cancer and a type of brain cancer known as glioblastoma, in which invasion is also mediated by ARF6."

Based on the findings of this study and other previous studies by the same group that show the importance of ARF6 in other biological processes, Navigen Inc., a Salt Lake City-based pharmaceutical and medical device company, is investigating new ARF6 inhibitors for pre-clinical studies.

Although SecinH3 itself is not suitable for treatment in human patients, it serves as a useful model compound for demonstrating that small-molecule inhibitors of ARF6 may have therapeutic value in melanoma, according to Shannon Odelberg, Ph.D., U of U assistant professor of internal medicine and neurobiology and anatomy, Navigen scientist, and a contributing author on the study. "Our findings are the first step toward developing potent therapies that may actually prevent or reduce melanoma metastasis," says Odelberg, also part of the Molecular Medicine Program at the University of Utah. "These new therapies could potentially be used in combination with current drugs to produce a more effective treatment for melanoma."

###

University of Utah Health Sciences: http://www.healthcare.utah.edu/publicaffairs/

Thanks to University of Utah Health Sciences for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127156/Inhibiting_protein_prevents_metastasis_to_lungs_in_mice

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Search Engine Optimization Scams That Should Be Avoided At All ...

A proven concept that helped many of the websites conducting their businesses in the internet is search engine optimization. This concept therefore is very popular to those wishing to sell their products or services online, and many professionals are jumping on the SEO bandwagon in providing these businesses the means to have favorable positions with the search engines. Although most of these so-called SEO services are legitimate and effective, a select number of scammers are likewise posing as search engine specialists online. It is a known fact that every niche in the web has its own gallery of rogues waiting in the wings to pounce on the uninitiated, and the field of SEO is no exception. These characters employ a variety of exploitative ways to milk money from inexperienced website owners, and most of these scams are founded upon the victims? lack of knowledge in the concept. The internet is teeming with false testimonials and hype from seemingly satisfied customers. The biggest SEO scam out there is the one that claims its client websites get included in first page results for every Google search made. This is every bit impossible since there is no exact process known that predicts the behavior of the Google algorithm. Of course, for the promise to be valid requires a loophole. If a prudent person takes the time to read the fine print, usually he or she will find outrageous and improbable conditions for the promise to be kept. In the case of the given SEO scam, this might mean an outrageous and improbable keyword or term that nobody, your website included, would ever dream of using. To place first page for these keywords is only natural since there is nobody else to compete with for it. But if your website has no use for those keywords, then the whole exercise is pointless anyway, and costly to boot.

Another scam to look out for is the promise of a guaranteed position in the online advertising niche through a focused SEO campaign. To show signs of the supposed campaign?s success, the scammer would usually rig a number of backlinks to the website in order for them to be listed among a search engine?s sponsored results. As soon as the client pays the consultation fees, the campaign instantly evaporates as well as the sponsored links. Genuine results could have been achieved for more or less the same cost, had the website used Google AdWords.

Lack of knowledge and a gung-ho attitude on the part of website owners are the preferred tools of the crook?s trade. This combination lends meaning to the words being robbed blind. An example can be found in the client who knows that links have SEO value, just not the kind that does. This client can end up paying a scammer for backlinks which the website can do without. Some crooks will simply use unfair SEO practices that can promptly get a website blacklisted in search engines. True, such techniques will improve the website?s ranking. But as soon as the search engine discovers the cheat, the website gets banned and the crook disappears with the money in tow.

A modest amount of common sense would save website owners a lot of grief. If something sounds too good to be true, it typically is. This adage applies even to search engine optimization. Basic understanding of SEO concepts, along with knowing enough not to give in to the temptation of greed will not hurt at all. The humiliation of being cheated, in addition to extensive damage to a website?s reputation and losing money should be adequate deterrents for the owner not to engage in shady SEO campaigns. Should a person call and promise huge success at very little cost to your website, be instantly wary. Always get a second opinion from someone who actually knows SEO, and do not cough up payment before getting results.

Source: http://blog.getrank.org/2013/03/search-engine-optimization-scams-that-should-be-avoided-at-all-costs/

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Home Improvements | Cota & Cota

Are you thinking about a home improvement project but don?t know where to begin? How about remodeling a bathroom, upgrading a heating system, or adding central air conditioning? We will be at the 35th Annual?HomeLife Expo in Hanover, NH next week to help you every step of the way!

When: March 15,16 & 17th

Where: Leverone Field House, Dartmouth College, Hanover, NH

Show Hours:

Friday, March 15 ? 2:00pm ? 9:00pm
Saturday, March 16 ? 10:00am ? 9:00pm
Sunday, March 17 ? 10:00am ? 4:00pm

Directions and parking information here!

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Source: http://www.cotaoil.com/2013/03/home-improvements/

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Monday, March 4, 2013

Violent start in Kenyan election; police killed

Daniel, 22, ties furniture to the roof of his car as he prepares to leave his house in the Mathare slum of Nairobi, Kenya Sunday, March 3, 2013 and head to his family's home in the countryside. Five years after more than 1,000 people were killed in election-related violence, Kenyans go to the polls on Monday to begin casting votes in a nationwide election seen as the country's most important - and complicated - in its 50-year history. (AP Photo/Mackenzie Knowles-Coursin)

Daniel, 22, ties furniture to the roof of his car as he prepares to leave his house in the Mathare slum of Nairobi, Kenya Sunday, March 3, 2013 and head to his family's home in the countryside. Five years after more than 1,000 people were killed in election-related violence, Kenyans go to the polls on Monday to begin casting votes in a nationwide election seen as the country's most important - and complicated - in its 50-year history. (AP Photo/Mackenzie Knowles-Coursin)

A supporter walks down steps plastered with campaign posters of Kenyan Presidential candidate Uhuru Kenyatta at his campaign's final rally at Uhuru Park in Nairobi, Kenya Saturday, March 2, 2013. Kenya's top two presidential candidates - Uhuru Kenyatta and Raila Odinga - held their final rallies Saturday before large and raucous crowds ahead of Monday's vote, which is the first nationwide election since Kenya's December 2007 vote descended into tribe-on-tribe violence that killed more than 1,000 people. (AP Photo/Ben Curtis)

Members of the Legio Maria religious movement pray for a peaceful election in Kisumu, Kenya Sunday, March 3, 2013. Clerics across Kenya gave sermons dedicated to peace on Sunday the day before a national election that some fear could descend into the same violence that engulfed the East African country after the disputed 2007 election. (AP Photo)

Kenyan Presidential candidate Uhuru Kenyatta, left, and his running mate William Ruto, right, greet the crowd at the final election rally of Kenyatta's The National Alliance party at Uhuru Park in Nairobi, Kenya Saturday, March 2, 2013. Kenya's top two presidential candidates - Uhuru Kenyatta and Raila Odinga - held their final rallies Saturday before large and raucous crowds ahead of Monday's vote, which is the first nationwide election since Kenya's December 2007 vote descended into tribe-on-tribe violence that killed more than 1,000 people. (AP Photo/Ben Curtis)

Orange Democratic Movement (ODM) Presidential candidate and current Prime Minister Raila Odinga addresses the crowd during a campaign rally at Nyayo National Stadium, Nairobi, Kenya, Saturday, March 2, 2013. Kenya's top two presidential candidates - Uhuru Kenyatta and Raila Odinga - held their final rallies Saturday before large and raucous crowds ahead of Monday's vote, which is the first nationwide election since Kenya's December 2007 vote descended into tribe-on-tribe violence that killed more than 1,000 people. (AP Photo/Khalil Senosi)

(AP) ? Five years after more than 1,000 people were killed in election-related violence, Kenyans on Monday began casting votes in a nationwide election seen as the country's most important ? and complicated ? in its 50-year history.

Police issued alerts late Sunday of impending attacks, and the violence began even before the voting. Police in the coastal city of Mombasa reported a 2 a.m. attack by a gang of dozens; early reports indicated several officers ? perhaps four or five ? were killed.

Multiple factors indicated violence was likely: The police said late Sunday that criminals were planning to dress in police uniforms and disrupt voting in some locations.

In addition, intelligence on the Somali-Kenya border indicated Somali militants planned to launch attacks; a secessionist group on the coast threatened ? and perhaps already carried out ? attacks; the tribes of the top two presidential candidates have a long history of tense relations; and 47 new governor races are being held, increasing the chances of electoral problems at the local level.

Perhaps most importantly, Uhuru Kenyatta, one of two top candidates for president, faces charges at the International Criminal Court for orchestrating the 2007-08 postelection violence. If he wins, the U.S. and Europe could scale back relations with Kenya, and Kenyatta may have to spend a significant portion of his presidency at The Hague.

Kenyatta's running mate, William Ruto, also faces charges at the ICC.

Kenyatta, a Kikuyu who is the son of Kenya's founding president, faces Raila Odinga, a Luo whose father was the country's first vice president. Polls show the two in a close race, with support for each in the mid-40-percent range. Eight candidates are running for president, making it likely Odinga and Kenyatta will be matched up in an April run-off, when tensions could be even higher.

Near the Somali border, Garissa County Commissioner Mohamed Ahmed Maalim said Sunday that officials intercepted communications that indicated terror attacks were planned, including explosive attacks and kidnappings. "They are planning to interrupt the elections, but we will not allow them do so," he said.

Maalim said soldiers are patrolling the region to prevent attacks from al-Shabab, the al-Qaida-linked Somali militant group. He said 300 specialized troops known as GSU are patrolling the Dadaab refugee camp, where more than 400,000 Somalis live.

In Mombasa, police officer Aggrey Adoli said Monday that police were attacked by a marauding gang while on patrol.

At the Nairobi Chapel, an evangelical church in the capital, three pastors took turns Sunday praising the attributes of some tribes, drawing cheers from the congregation. The Kikuyus were praised for being entrepreneurial, the Luos for valuing education, and the Kalenjins ? Ruto's tribe ? for their loyalty.

"Tomorrow we celebrate our cultural diversity as a nation," Nick Korir said in his sermon.

"We ask you to shame all prophets of doom," a cleric at an evangelical church in Nairobi called Mavuno told a packed congregation. "This is a country we are all proud of despite the divisions that people talk about. There is a Kenya after tomorrow."

In the weeks leading up to Monday's vote, described by Odinga as the most consequential since independence from the British in 1963, peace activists and clerics have been praying that this time the election is peaceful despite lingering tensions.

Odinga's acrimonious loss to President Mwai Kibaki in 2007 triggered violence that ended only after the international community stepped in. Odinga was named prime minister in a coalition government led by Kibaki, with Kenyatta named deputy prime minister.

The candidates held their final rallies Saturday, a day of political attacks and denials following published comments in the Financial Times attributed to Odinga that election violence could be worse than 2007-08 if the vote is rigged.

The Financial Times on Sunday said that its story, because of an editing error, "may have left the incorrect impression" that Odinga "would not respect the result of a free and fair presidential election. We are happy to be able to clarify this point."

Some 99,000 police officers will be on duty during an election in which some 14 million people are expected to vote. Kenyans will also be electing new lawmakers, governors and other officials.

Kenyatta, 51, the son of Jomo Kenyatta, the country's founding president, is one of the country's wealthiest men. He studied at Amherst College in the U.S. before returning home to become a businessman and later his father's political heir.

In 2011 Forbes magazine listed him as the wealthiest Kenyan, worth at least $500 million, although he was dropped from a subsequent list because his personal wealth was hard to separate from that of his close relatives. The Kenyattas are said to own hundreds of thousands of acres of prime land across the country, a controversial point in a nation where millions do not own even a small plot of land.

Gladwell Otieno, a Kenyan who runs a think tank called The Africa Center for Open Governance, said it would "be difficult for (Kenyatta) to claim that he can do much" to tackle Kenya's historical land problem. But despite the baggage of wealth and the ICC charges, Kenyatta's team has done a good job of marketing him as "a youthful candidate" of hope, Otieno said.

"Our main concern has been the fact that he is indicted at the ICC," Otieno said. "A government led by him would immediately be paralyzed."

Odinga, 68, who has been prime minister since 2008, believes he was cheated out of victory in the last election. Odinga's refusal to accept the results in 2007 helped fuel tribal tensions, with many here seeing Kibaki's win as another example of the Kikuyus' overly broad influence.

A win by Odinga would make him the country's first Luo president, a feat never accomplished by his father, Oginga Odinga, who was Kenya's first vice president and himself a hero of the anti-colonial movement. The elder Odinga fell out with Jomo Kenyatta, Kenya's first president, straining Kikuyu-Luo relations for decades.

In a rally Friday in Kisumu, Odinga's hometown and the biggest Luo-dominated city, Odinga repeatedly used words like "freedom" and "change" to emphasize the epochal moment it would be for his people if he wins.

"Be prepared for freedom," he said. "This country is at the verge of total liberation."

___

Associated Press reporter Daud Yussuf in Garissa contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-03-03-Kenya-Election/id-24dee83fc31243e9b26961ad3586defc

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2nd Jonah Lehrer book being pulled from shelves

NEW YORK (AP) ? A second Jonah Lehrer book is being pulled.

Houghton Mifflin Harcourt announced Friday that Lehrer's "How We Decide," originally published in 2009, is being taken "off sale." Spokeswoman Lori Glazer said the decision followed an internal review, but she didn't elaborate.

Lehrer's best-selling "Imagine" was withdrawn last year after Tablet Magazine reported that Lehrer had manipulated and fabricated Bob Dylan quotes. At the same time, he resigned as a staff writer for The New Yorker.

Glazer said Friday that the publisher will continue to sell a third Lehrer book, "Proust Was a Neuroscientist," which was released in 2007.

The 31-year-old Lehrer had been a popular author and speaker, specializing in books and essays about how the mind works. But he also has been criticized for sloppy scholarship and faulty reasoning, and he admitted recycling his own journalism for separate publications.

During a recent speech in Miami, he blamed himself for "arrogance" and "carelessness" and expressed hope that he could revive his career.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-03-01-Books-Jonah%20Lehrer/id-60c69da6377a40498ce42e3008db0927

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Obama renews offer to cut social safety nets in big budget deal: aide

WASHINGTON (Reuters) - President Barack Obama raised anew the issue of cutting entitlements such as Medicare and Social Security as a way out of damaging budget cuts, a White House official said on Sunday, as both sides in Washington tried to limit a fiscal crisis that may soon hit millions of Americans.

Signaling he might be ready to explore a compromise to end automatic spending cuts that began late Friday, Obama mentioned reforming these entitlement programs in calls with lawmakers from both parties on Saturday afternoon.

"He's reaching out to Democrats who understand we have to make serious progress on long-term entitlement reform, and Republicans who realize that if we had that type of entitlement reform, they'd be willing to have tax reform that raises revenues to lower the deficit," White House senior economic official Gene Sperling said on Sunday on the CNN program "State of the Union."

Republicans have long argued that the only way to tame budget deficits over the long haul is by slowing the cost of sprawling social safety net programs.

These include the Social Security retirement program and Medicare and Medicaid healthcare programs for the elderly, disabled and poor that are becoming more expensive as a large segment of the U.S. population hits retirement age.

While Obama also has proposed some savings on these programs, he has insisted that significant new tax revenues be part of the deficit-reduction formula, an idea Republicans so far reject.

Budget fights in Congress took their most serious turn in years on Friday when $85 billion in indiscriminate spending cuts known as "sequestration" began to kick in after both parties failed to agree on how to stop them.

Democrats predict the automatic cuts could soon cause air-traffic delays, meat shortages as food safety inspections slow down, and hundreds of thousands of furloughs for federal workers.

Neither Sperling nor White House spokesmen would provide further details on the Obama's conversations on Saturday with members of Congress.

Obama's mention of entitlement reform may help bring Republicans to the table to halt the cuts. Republican leaders also made soothing noises on Sunday about the need to avoid a government shutdown on March 27, when funding runs out for most federal programs.

BOEHNER'S MAXIMUM EFFORT

House of Representatives Speaker John Boehner, interviewed on NBC's "Meet the Press," said he "absolutely" would do whatever it takes to keep the government operating. Toward that end, he will seek House passage this week of a "continuing resolution" to fund the government through September 30, when the fiscal year ends.

Lately, some rank-and-file Democrats and Republicans have been sending signals that they are willing to compromise to end a two-year-old deadlock over tax and entitlement reforms.

Last week, conservative Republican Senator Lindsey Graham of South Carolina said he was open to raising $600 billion in new tax revenue if Democrats accepted significant changes to Medicare and Medicaid as part of a long-term budget deal.

A few days later, liberal Democratic Senator Ben Cardin of Maryland told Reuters that he had discussed with Senate Majority Leader Harry Reid the possibility of replacing the automatic spending cuts with a mix of entitlement reforms and tax increases.

"Democrats know we have to do entitlement reforms and Republicans know they have to do revenues (increases)," Cardin said.

Now that they are in place, the $85 billion in spending cuts must be carried out by September 30 if no alternative is found. Half of those cuts would hit the military with the rest scattered over thousands of other domestic programs.

Economists have warned that such a heavy dose of belt tightening over such a short period will slow U.S. economic growth and potentially cost 750,000 jobs.

Speaking of the search for alternatives, Boehner said on "Meet the Press:" "I don't think anyone quite understands how it gets resolved."

No matter how Obama and Congress resolve the 2013 battle, this round of automatic spending cuts is only one of a decade's worth of annual cuts totaling $1.2 trillion mandated by the sequestration law.

DEEP DIVISIONS STILL

Deep divisions between Democrats and Republicans have soured previous negotiations.

Slamming the door on Democrats' demands for new tax hikes, Boehner said that Obama "got $650 billion of higher taxes on the American people on January the first. How much more does he want?" He was referring to the higher tax rate that began in the new year on households making more than $450,000 a year.

"It's time for the president and Senate Democrats to get serious about the long-term spending problem that we have," Boehner said.

In the meantime, both Democrats and Republicans were hoping to win the immediate fight over the automatic spending cuts so that they are best positioned in any upcoming battles over long-term budget deficits.

Senate Republican leader Mitch McConnell on Sunday played down the severity of the automatic cuts, describing them as modest.

"We're willing to talk to him (Obama) about reconfiguring the same amount of spending reduction over the next six months," McConnell said on CNN. "The American people look at this and say, 'Gee, I've had to cut my budget more than this,' - probably on numerous occasions over the last four years because we've had such a tepid economy now for four long years."

At the heart of Washington's persistent fiscal crises is disagreement over how to slash the budget deficit and gain control of the $16.7 trillion national debt, bloated over the years by wars in Iraq and Afghanistan and government stimulus for the ailing economy.

Government red ink also rose over the last decade after the enactment of across-the-board tax cuts in 2001 and 2003 secured by President George W. Bush.

(Additional reporting by Will Dunham and Philip Barbara; Editing by Alistair Bell and Philip Barbara)

Source: http://news.yahoo.com/spending-cut-showdown-threatens-obamas-second-term-agenda-025029989--business.html

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Sunday, March 3, 2013

ScienceDaily: Living Well News

ScienceDaily: Living Well Newshttp://www.sciencedaily.com/news/living_well/ Stories about health and wellness, lifestyle issues and trends, family concerns and other topics about everyday life.en-usSun, 03 Mar 2013 02:26:06 ESTSun, 03 Mar 2013 02:26:06 EST60ScienceDaily: Living Well Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/living_well/ For more science articles, visit ScienceDaily.Facebook 'Likes' a good indicator of quality hospital carehttp://www.sciencedaily.com/releases/2013/03/130301123312.htm While those active on social media aren't shy about expressing opinions on their Facebook pages, how much do their "Likes" really reflect the quality of an organization? A new study shows that Facebook "Likes" were indeed an indicator of hospital quality and patient satisfaction.Fri, 01 Mar 2013 12:33:33 ESThttp://www.sciencedaily.com/releases/2013/03/130301123312.htmPregnancy permanently changes foot sizehttp://www.sciencedaily.com/releases/2013/03/130301122306.htm A new study of women's feet during and after pregnancy shows that arch height and arch rigidity decrease significantly from early pregnancy to five months after childbirth, causing corresponding increases in foot length that appear to be permanent.Fri, 01 Mar 2013 12:23:23 ESThttp://www.sciencedaily.com/releases/2013/03/130301122306.htmCancer doesn't change young girls' desire to have children, study showshttp://www.sciencedaily.com/releases/2013/03/130301034833.htm Researchers have found that healthy adolescent females have predetermined expectations for becoming parents in the future, but have concerns about fertility and childbearing should they develop a life-threatening illness, such as cancer.Fri, 01 Mar 2013 03:48:48 ESThttp://www.sciencedaily.com/releases/2013/03/130301034833.htmProblems with identifying meat? The answer is to check the barcodehttp://www.sciencedaily.com/releases/2013/02/130228194659.htm Want to know what you are eating? DNA barcodes can be used to identify even very closely related species, finds a new article. Results from the study show that the labelling of game meat in South Africa is very poor with different species being substituted almost 80 percent of the time.Thu, 28 Feb 2013 19:46:46 ESThttp://www.sciencedaily.com/releases/2013/02/130228194659.htmBrain can't cope with making a left-hand turn and talking on hands-free cell phonehttp://www.sciencedaily.com/releases/2013/02/130228124142.htm Most serious traffic accidents occur when drivers are making a left-hand turn at a busy intersection. When those drivers are also talking on a hands-free cell phone, "that could be the most dangerous thing they ever do on the road," said an expert.Thu, 28 Feb 2013 12:41:41 ESThttp://www.sciencedaily.com/releases/2013/02/130228124142.htmAction video games boost reading skills, study of children with dyslexia suggestshttp://www.sciencedaily.com/releases/2013/02/130228124132.htm Much to the chagrin of parents who think their kids should spend less time playing video games and more time studying, time spent playing action video games can actually make dyslexic children read better, new research suggests. In fact, 12 hours of video game play did more for reading skills than is normally achieved with a year of spontaneous reading development or demanding traditional reading treatments.Thu, 28 Feb 2013 12:41:41 ESThttp://www.sciencedaily.com/releases/2013/02/130228124132.htm'Crazy-busy' Canadians under pressure on the jobhttp://www.sciencedaily.com/releases/2013/02/130228103458.htm Having more control in the workplace can have negative consequences for individuals, but it depends on the form of job control. Having control over one's work schedule and job autonomy are associated with lower levels of job pressure.Thu, 28 Feb 2013 10:34:34 ESThttp://www.sciencedaily.com/releases/2013/02/130228103458.htmEating junk food while pregnant may make your child a junk food addicthttp://www.sciencedaily.com/releases/2013/02/130228103443.htm A healthy diet during pregnancy is critical to the future health of your children. New research suggests that pregnant mothers who consume junk food cause developmental changes of the opioid signaling pathway in the brains of their unborn children. Consequently, these children are less sensitive to opioids released upon consumption of foods high in fat and sugar, and need to eat more to achieve a "feel good" response.Thu, 28 Feb 2013 10:34:34 ESThttp://www.sciencedaily.com/releases/2013/02/130228103443.htmReading, writing, arithmetic, and aerobics: Evaluating the new 'R' in academic performancehttp://www.sciencedaily.com/releases/2013/02/130228080547.htm Although the long-term consequences of childhood obesity are well documented, some school districts have reduced physical education classes to devote more time to the three Rs in education -- reading, writing, and arithmetic. However, there is new evidence that leaving out an important fourth R -- aerobics -- could actually be counterproductive for increasing test scores. A new study studied the associations between aerobic fitness, body mass index, and passing scores on standardized math and reading tests.Thu, 28 Feb 2013 08:05:05 ESThttp://www.sciencedaily.com/releases/2013/02/130228080547.htmWhy some people get zits and others don'thttp://www.sciencedaily.com/releases/2013/02/130228080135.htm Researchers have discovered that acne bacteria contain "bad" strains associated with pimples and "good" strains that may protect the skin. The findings could lead to a myriad of new therapies to prevent and treat the disfiguring skin disorder.Thu, 28 Feb 2013 08:01:01 ESThttp://www.sciencedaily.com/releases/2013/02/130228080135.htmCan your breath identify stress?http://www.sciencedaily.com/releases/2013/02/130227225636.htm The perennial stress-buster -- a deep breath -- could become stress-detector. According to a new pilot study, there are six markers in the breath that could be candidates for use as indicators of stress.Wed, 27 Feb 2013 22:56:56 ESThttp://www.sciencedaily.com/releases/2013/02/130227225636.htmSitting less and moving about more could be more important than vigorous exercise to reduce risk of type 2 diabeteshttp://www.sciencedaily.com/releases/2013/02/130227183526.htm New research reveals that individuals at high risk of developing type 2 diabetes would benefit from being told to sit less and move around more often -- rather than simply exercising regularly. The experts suggest that reducing sitting time by 90 minutes in total per day could lead to important health benefits.Wed, 27 Feb 2013 18:35:35 ESThttp://www.sciencedaily.com/releases/2013/02/130227183526.htmHeading a soccer ball may affect cognitive performancehttp://www.sciencedaily.com/releases/2013/02/130227183458.htm Sports-related head injuries are a growing concern, and new research suggests that even less forceful actions like 'heading' a soccer ball may cause changes in performance on certain cognitive tasks, according to new research.Wed, 27 Feb 2013 18:34:34 ESThttp://www.sciencedaily.com/releases/2013/02/130227183458.htmHigher indoor humidity inactivates flu virus particleshttp://www.sciencedaily.com/releases/2013/02/130227183456.htm Higher humidity levels indoors can significantly reduce the infectivity of influenza virus particles released by coughing, according to new research.Wed, 27 Feb 2013 18:34:34 ESThttp://www.sciencedaily.com/releases/2013/02/130227183456.htmPraising children for their personal qualities may backfirehttp://www.sciencedaily.com/releases/2013/02/130227183316.htm Praising children, especially those with low self-esteem, for their personal qualities rather than their efforts may make them feel more ashamed when they fail, according to new research.Wed, 27 Feb 2013 18:33:33 ESThttp://www.sciencedaily.com/releases/2013/02/130227183316.htmResearch explores factors that impact adolescent mental healthhttp://www.sciencedaily.com/releases/2013/02/130227151258.htm Research indicates that half of all lifetime cases of mental illness begin by age 14, well before adulthood. Three new studies investigate the cognitive, genetic and environmental factors that may contribute to mental health disorders in adolescence.Wed, 27 Feb 2013 15:12:12 ESThttp://www.sciencedaily.com/releases/2013/02/130227151258.htmLipid researcher, 98, reports on the dietary causes of heart diseasehttp://www.sciencedaily.com/releases/2013/02/130227151254.htm A 98-year-old researcher argues that, contrary to decades of clinical assumptions and advice to patients, dietary cholesterol is good for your heart -- unless that cholesterol is unnaturally oxidized (by frying foods in reused oil, eating lots of polyunsaturated fats, or smoking).Wed, 27 Feb 2013 15:12:12 ESThttp://www.sciencedaily.com/releases/2013/02/130227151254.htmName your neighborhood, define your health?http://www.sciencedaily.com/releases/2013/02/130227134342.htm Does your neighborhood really define health? Most of us make a choice between suburbs, countryside, or city and settle down. But others, particularly those living in poverty, don?t always get to make that choice ?- the choice that could actually determine our quality and length of life. So how does this choice affect our health?Wed, 27 Feb 2013 13:43:43 ESThttp://www.sciencedaily.com/releases/2013/02/130227134342.htmContaminated diet contributes to exposure to endocrine-disrupting chemicals: Phthalates and BPAhttp://www.sciencedaily.com/releases/2013/02/130227121903.htm While water bottles may tout BPA-free labels and personal care products declare phthalates not among their ingredients, these assurances may not be enough. According to a new study, we may be exposed to these chemicals in our diet, even if our diet is organic and we prepare, cook, and store foods in non-plastic containers. Children may be most vulnerable.Wed, 27 Feb 2013 12:19:19 ESThttp://www.sciencedaily.com/releases/2013/02/130227121903.htmTrust makes you delusional and that's not all bad: Trusting partners remember transgressions in ways that benefit the relationshiphttp://www.sciencedaily.com/releases/2013/02/130227113100.htm New research is the first to systematically examine the role of trust in biasing memories of transgressions in romantic partnerships. People who are highly trusting tended to remember transgressions in a way that benefits the relationship, remembering partner transgressions as less severe than they originally reported. People low on trust demonstrated the opposite pattern, remembering partner transgressions as being more severe than how they originally reported.?Wed, 27 Feb 2013 11:31:31 ESThttp://www.sciencedaily.com/releases/2013/02/130227113100.htmDefining the new normal in aginghttp://www.sciencedaily.com/releases/2013/02/130227113058.htm Researcher says terms such as "normal," "healthy" or "successful" aging can prejudice our views of seniors.Wed, 27 Feb 2013 11:30:30 ESThttp://www.sciencedaily.com/releases/2013/02/130227113058.htmNew studies link gene to selfish behavior in kids, find other children natural givershttp://www.sciencedaily.com/releases/2013/02/130227102940.htm Most parents would agree that raising a generous child is an admirable goal -- but how, exactly, is that accomplished? New results shed light on how generosity and related behaviors -- such as kindness, caring and empathy -- develop, or don't develop, in children from 2 years old through adolescence.Wed, 27 Feb 2013 10:29:29 ESThttp://www.sciencedaily.com/releases/2013/02/130227102940.htmMarried opposite-sex couples have better overall health than same-sex couples who live togetherhttp://www.sciencedaily.com/releases/2013/02/130227102100.htm Same-sex couples who live together have worse health than married opposite-sex couples and similar health as opposite-sex couples who are living together (after adjusting for socioeconomic differences), according to a new study.Wed, 27 Feb 2013 10:21:21 ESThttp://www.sciencedaily.com/releases/2013/02/130227102100.htmPessimism about the future may lead to longer, healthier lifehttp://www.sciencedaily.com/releases/2013/02/130227101929.htm Older people who have low expectations for a satisfying future may be more likely to live longer, healthier lives than those who see brighter days ahead, according to new research.Wed, 27 Feb 2013 10:19:19 ESThttp://www.sciencedaily.com/releases/2013/02/130227101929.htmDo thin models and celebrities really help sell to women?http://www.sciencedaily.com/releases/2013/02/130227085840.htm Advertisers who put images of female celebrities and models next to their products spark scorn rather than shopping, according to new research.Wed, 27 Feb 2013 08:58:58 ESThttp://www.sciencedaily.com/releases/2013/02/130227085840.htmToo much vitamin D during pregnancy can cause food allergies, research suggestshttp://www.sciencedaily.com/releases/2013/02/130227085838.htm Pregnant women should avoid taking vitamin D supplements, new research suggests. Substitution appears to raise the risk of children developing a food allergy after birth.Wed, 27 Feb 2013 08:58:58 ESThttp://www.sciencedaily.com/releases/2013/02/130227085838.htmSame-sex cohabitors less healthy than those in heterosexual marriages, study suggestshttp://www.sciencedaily.com/releases/2013/02/130227085706.htm Same-sex cohabitors report worse health than people of the same socioeconomic status who are in heterosexual marriages, according to a new study, which may provide fuel for gay marriage proponents.Wed, 27 Feb 2013 08:57:57 ESThttp://www.sciencedaily.com/releases/2013/02/130227085706.htmIncreased risk of sleep disorder narcolepsy in children who received swine flu vaccinehttp://www.sciencedaily.com/releases/2013/02/130226194006.htm A study finds an increased risk of narcolepsy in children and adolescents who received the A/H1N1 2009 influenza vaccine (Pandemrix) during the pandemic in England.Tue, 26 Feb 2013 19:40:40 ESThttp://www.sciencedaily.com/releases/2013/02/130226194006.htmTexting Gloves Dangerous in Winter, Says experthttp://www.sciencedaily.com/releases/2013/02/130226141235.htm Fingers are one of the first body parts to suffer from the cold and popular fingerless texting gloves can lead to frostbite and in worst cases, amputation, says an expert.Tue, 26 Feb 2013 14:12:12 ESThttp://www.sciencedaily.com/releases/2013/02/130226141235.htmTexting becoming a pain in the neckhttp://www.sciencedaily.com/releases/2013/02/130226101259.htm Orthopedic surgeon, spine specialist says excessive leaning head forward and down, while looking at a phone or other mobile device could result in what some people call ?text neck.?Tue, 26 Feb 2013 10:12:12 ESThttp://www.sciencedaily.com/releases/2013/02/130226101259.htmSleep reinforces learning: Children?s brains transform subconsciously learned material into active knowledgehttp://www.sciencedaily.com/releases/2013/02/130226081155.htm During sleep, our brains store what we have learned during the day a process even more effective in children than in adults, new research shows.Tue, 26 Feb 2013 08:11:11 ESThttp://www.sciencedaily.com/releases/2013/02/130226081155.htmMediterranean diet helps cut risk of heart attack, stroke: Results of PREDIMED study presentedhttp://www.sciencedaily.com/releases/2013/02/130225181536.htm Results of a major study aimed at assessing the efficacy of the Mediterranean diet in the primary prevention of cardiovascular diseases show that such a diet supplemented with extra-virgin olive oil or tree nuts reduces by 30 percent the risk of suffering a cardiovascular death, a myocardial infarction or a stroke.Mon, 25 Feb 2013 18:15:15 ESThttp://www.sciencedaily.com/releases/2013/02/130225181536.htmDoing good is good for you: Volunteer adolescents enjoy healthier heartshttp://www.sciencedaily.com/releases/2013/02/130225162229.htm Giving back through volunteering is good for your heart, even at a young age, according to researchers.Mon, 25 Feb 2013 16:22:22 ESThttp://www.sciencedaily.com/releases/2013/02/130225162229.htmTargeting CPR education in high-risk neighborhoods could save more liveshttp://www.sciencedaily.com/releases/2013/02/130225153046.htm Targeting CPR education in high-risk neighborhoods could increase the number of bystanders giving CPR and decrease deaths from cardiac arrest, according to a new statement.Mon, 25 Feb 2013 15:30:30 ESThttp://www.sciencedaily.com/releases/2013/02/130225153046.htmGender gap disappears in school math competitionshttp://www.sciencedaily.com/releases/2013/02/130225153029.htm The idea that boys are better at math and in competitions has persisted for a long time - primarily because of the competition format. A new study shows that competitions that extend beyond a single round result in parity between the sexes.Mon, 25 Feb 2013 15:30:30 ESThttp://www.sciencedaily.com/releases/2013/02/130225153029.htmGlobal surveys show environment ranks low among public concernshttp://www.sciencedaily.com/releases/2013/02/130225131541.htm A newly released international study reveals that the issue of climate change is not a priority for people in the United States and around the world. The surveys showed that when asked to rank priority worries, people were five times more likely to point to the economy over the environment.Mon, 25 Feb 2013 13:15:15 ESThttp://www.sciencedaily.com/releases/2013/02/130225131541.htmMoments of spirituality can induce liberal attitudes, researchers findhttp://www.sciencedaily.com/releases/2013/02/130225131532.htm People become more politically liberal immediately after practising a spiritual exercise such as meditation, researchers have found.Mon, 25 Feb 2013 13:15:15 ESThttp://www.sciencedaily.com/releases/2013/02/130225131532.htmMemory strategy may help depressed people remember the good timeshttp://www.sciencedaily.com/releases/2013/02/130225122047.htm New research highlights a memory strategy that may help people who suffer from depression in recalling positive day-to-day experiences.Mon, 25 Feb 2013 12:20:20 ESThttp://www.sciencedaily.com/releases/2013/02/130225122047.htmA question of accountability: What happens when employees are left in the dark?http://www.sciencedaily.com/releases/2013/02/130225112320.htm All employees are accountable for something, but very few fully understand exactly what they are accountable for, according to a new study.Mon, 25 Feb 2013 11:23:23 ESThttp://www.sciencedaily.com/releases/2013/02/130225112320.htmCatfight? Workplace conflicts between women get bad raphttp://www.sciencedaily.com/releases/2013/02/130225092248.htm A new study suggests troubling perceptions exist when it comes to women involved in disputes at work.Mon, 25 Feb 2013 09:22:22 ESThttp://www.sciencedaily.com/releases/2013/02/130225092248.htmMost babies slow to grow catch up by early teenshttp://www.sciencedaily.com/releases/2013/02/130225092246.htm New research shows that most babies who are slow to put on weight in the first nine months of life have caught up to within the normal range by the age of 13, but remain lighter and shorter than many of their peers. There are significant differences in the pattern of "catchup," depending on the infant's age when the slow weight gain occurs.Mon, 25 Feb 2013 09:22:22 ESThttp://www.sciencedaily.com/releases/2013/02/130225092246.htmParents talking about their own drug use to children could be detrimentalhttp://www.sciencedaily.com/releases/2013/02/130222083127.htm Parents know that one day they will have to talk to their children about drug use. The hardest part is to decide whether or not talking about ones own drug use will be useful in communicating an antidrug message. Recent research found that children whose parents did not disclose drug use, but delivered a strong antidrug message, were more likely to exhibit antidrug attitudes.Fri, 22 Feb 2013 08:31:31 ESThttp://www.sciencedaily.com/releases/2013/02/130222083127.htmSmarter lunchrooms make lunch choices child's playhttp://www.sciencedaily.com/releases/2013/02/130222083125.htm In Jan. 2012, the United States Department of Agriculture passed a series of regulations designed to make school lunches more nutritious, which included requiring schools to increase whole grain offerings and making students select either a fruit or vegetable with their purchased lunch. However, children cannot be forced to eat these healthier lunches. In a new study, researchers determined that small, inexpensive changes to school cafeterias influenced the choice and consumption of healthier foods.Fri, 22 Feb 2013 08:31:31 ESThttp://www.sciencedaily.com/releases/2013/02/130222083125.htmInfluenza study: Meet virus' new enemyhttp://www.sciencedaily.com/releases/2013/02/130221194241.htm Virologists have discovered a new class of molecular compounds capable of killing the influenza virus. Working on the premise that too much of a good thing can be a killer, the scientists have advanced previous researchers' methods of manipulating an enzyme that is key to how influenza replicates and spreads. The new compounds will lead to a new generation of anti-influenza drugs that the virus' strains can't adapt to, and resist, as easily as they do Tamiflu.Thu, 21 Feb 2013 19:42:42 ESThttp://www.sciencedaily.com/releases/2013/02/130221194241.htmScientists make older adults less forgetful in memory testshttp://www.sciencedaily.com/releases/2013/02/130221143946.htm Scientists have found compelling evidence that older adults can eliminate forgetfulness and perform as well as younger adults on memory tests. The cognitive boost comes from a surprising source -- a distraction learning strategy.Thu, 21 Feb 2013 14:39:39 ESThttp://www.sciencedaily.com/releases/2013/02/130221143946.htmShould grandma join Facebook? It may give her a cognitive boost, study findshttp://www.sciencedaily.com/releases/2013/02/130221143912.htm Preliminary research findings suggest learning to use Facebook may help give adults older than 65 a cognitive boost. The study shows that seniors who learned to use Facebook saw improvements in their ability to continuously monitor and quickly add or delete the contents of their working memory.Thu, 21 Feb 2013 14:39:39 ESThttp://www.sciencedaily.com/releases/2013/02/130221143912.htmHeavy backpacks may damage nerves, muscles and skeleton, study suggestshttp://www.sciencedaily.com/releases/2013/02/130221141604.htm Damage to muscles and the skeleton is the frequent consequence of carrying heavy backpacks and occupational gear on our backs. New research confirms that damage to the nerves that travel through the neck and shoulders is also a serious risk.Thu, 21 Feb 2013 14:16:16 ESThttp://www.sciencedaily.com/releases/2013/02/130221141604.htmWanted: A life outside the workplacehttp://www.sciencedaily.com/releases/2013/02/130221115801.htm New research suggests the growing number of workers who are single and without children have trouble finding the time or energy to participate in non-work interests, just like those with spouses and kids.Thu, 21 Feb 2013 11:58:58 ESThttp://www.sciencedaily.com/releases/2013/02/130221115801.htmIn rich and poor nations, giving makes people feel better than getting, research findshttp://www.sciencedaily.com/releases/2013/02/130221104357.htm Feeling good about spending money on someone else rather than for personal benefit may be a universal response among people in both impoverished countries and rich nations, according to new research.Thu, 21 Feb 2013 10:43:43 ESThttp://www.sciencedaily.com/releases/2013/02/130221104357.htmAccidental poisonings leading cause of deaths at home, study findshttp://www.sciencedaily.com/releases/2013/02/130221104157.htm An increasing number of people die from unintentional home injury, in large part due to accidental drug overdose, according to a new study.Thu, 21 Feb 2013 10:41:41 ESThttp://www.sciencedaily.com/releases/2013/02/130221104157.htmSocial capital -- the benefit of Facebook 'friends'http://www.sciencedaily.com/releases/2013/02/130221084618.htm Intense Facebook usage is found to have a positive effect on psychological well-being, according to a new study.?Thu, 21 Feb 2013 08:46:46 ESThttp://www.sciencedaily.com/releases/2013/02/130221084618.htmWhen children can hop on one leg: Motor development in children under 5 can now be tested reliablyhttp://www.sciencedaily.com/releases/2013/02/130221084602.htm Researchers have determined normative data for different exercises such as hopping or running. This enables parents and experts to gauge the motor skills of young children for the first time objectively and thus identify abnormalities at an early stage.Thu, 21 Feb 2013 08:46:46 ESThttp://www.sciencedaily.com/releases/2013/02/130221084602.htmTalking about being old is important indicator of body dissatisfactionhttp://www.sciencedaily.com/releases/2013/02/130220203711.htm Similar to talking about being fat, talking about being old is an important an indicator of body dissatisfaction, shows new research. Body dissatisfaction is known to be correlated with, and predictive of, physical and mental health problems including binge eating, emotional eating, stress, low self-esteem, depression, and use of unhealthy weight control behaviors. High levels of talking about weight and being fat, ?fat talk?, is known to be a good indicator of body dissatisfaction.Wed, 20 Feb 2013 20:37:37 ESThttp://www.sciencedaily.com/releases/2013/02/130220203711.htmScrap 'unwinnable' drugs war and divert funds into curbing global antibiotic misuse, experts sayhttp://www.sciencedaily.com/releases/2013/02/130220184955.htm Governments around the world should stop squandering resources fighting an "unwinnable war" against illegal drugs, such as cocaine and heroin. Instead, they should use the cash to curb antibiotic misuse, which poses a far more serious threat to human health, claims a leading ethicist.Wed, 20 Feb 2013 18:49:49 ESThttp://www.sciencedaily.com/releases/2013/02/130220184955.htmMosquitoes exposed to DEET once are less repelled by it a few hours later, study claimshttp://www.sciencedaily.com/releases/2013/02/130220184949.htm Mosquitoes are able to ignore the smell of the insect repellent DEET within a few hours of being exposed to it, according to new research.Wed, 20 Feb 2013 18:49:49 ESThttp://www.sciencedaily.com/releases/2013/02/130220184949.htmBackground checks, permanent records needed for all firearm transfers, not just gun sales by retailers, experts urgehttp://www.sciencedaily.com/releases/2013/02/130220163633.htm Gun violence in the United States can be substantially reduced if Congress expands requirements for background checks on retail gun sales to cover firearm transfers between private parties, a new report concludes.Wed, 20 Feb 2013 16:36:36 ESThttp://www.sciencedaily.com/releases/2013/02/130220163633.htmBullied children can suffer lasting psychological harm as adultshttp://www.sciencedaily.com/releases/2013/02/130220163629.htm Bullied children grow into adults who are at increased risk of developing anxiety disorders, depression and suicidal thoughts, according to a new study.Wed, 20 Feb 2013 16:36:36 ESThttp://www.sciencedaily.com/releases/2013/02/130220163629.htmEmployees shed pounds in worksite-based weight loss intervention with behavioral counselinghttp://www.sciencedaily.com/releases/2013/02/130220163557.htm Workplace-based programs that include dietary advice coupled with behavioral counseling appear to be a promising approach for men and women with significant weight loss goals, based on the results of a pilot study. Employees enrolled in the intervention arm of a randomized controlled trial lost on average, 18 pounds over a six-month period compared to a two pound weight gain in a control group.Wed, 20 Feb 2013 16:35:35 ESThttp://www.sciencedaily.com/releases/2013/02/130220163557.htmSeparated bike lanes, slower vehicle speeds greatly reduce bicycle injurieshttp://www.sciencedaily.com/releases/2013/02/130220131744.htm Using your bicycle to commute to work has numerous health and environmental benefits. Yet, the largest Canadian study on cycling injuries suggests cyclists are at risk of injury due to the lack of cycling infrastructure in large urban centers.Wed, 20 Feb 2013 13:17:17 ESThttp://www.sciencedaily.com/releases/2013/02/130220131744.htmResveratrol shows promise to protect hearing, cognitionhttp://www.sciencedaily.com/releases/2013/02/130220131742.htm Resveratrol, a substance found in red grapes and red wine, may have the potential to protect against hearing and cognitive decline, according to a new study.Wed, 20 Feb 2013 13:17:17 ESThttp://www.sciencedaily.com/releases/2013/02/130220131742.htm

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